How LPS prevents or promotes development of asthma and allergic disease by airborne allergens

Many experiments show that exposure to LPS during exposure to environmental allergens protects against developing asthma or allergic disease. Yet other numerous experiments show that the presence of LPS during exposure to environmental allergens does the opposite — it promotes the development of asthma and other allergic disease. Now researchers detail a series of mechanistic steps that reveal a surprising answer — the key to LPS’ promoting or preventing the allergic reaction lies in the allergen itself.

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